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| MOU with Saveetha University of India for Joint Biomedical Research - Sep 23, 2007 |
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| Received Top-Tier Professional Enterprise Award |
| [...] Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Research & Development: Future Vision
Bio-scaffold International (BSI) is continuing its effort in R&D of the process methodology of scaffold to tailor the properties for new applications that are non-load bearing tissues as well as expand the application of current scaffold beyond non-load bearing soft tissues. BSI is hoping to develop new synthetic material bone substitutes, properties of which can be matched to bone properties to aid easy integration as well as shorten the healing time. Another application currently being explored is to enhance current scaffolds with additional features to extend the applications beyond the current one. BSI is also working towards delivering a scaffold for segmental repair and augmentation by controlling the process parameters to have good dimensional control and controlled degradation. Currently, scaffolds for hard tissue are either made using solid metals and ceramics ! especially for elderly patients where self healing is difficult. However, one of the limitation is the difference in mechanical properties between the hard tissue and that of the permanent scaffold, i.e., Cortical bone has a modulus of 7 - 30 GPa while most commonly used implants (permanent scaffolds) have modulus that are typically 4 to 5 times the bone modulus leading to complications such as stress shielding. BSI is also aiming at developing a porous implant (permanent scaffold) with tailored mechanical properties using the biomaterials currently used to overcome this limitation.
Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Research & Development: Our TechnologyBio-scaffold International (BSI) is a home grown Biotechnology company based in Singapore has developed a process to fabricate non-load bearing tissue scaffolds, specially for Dental sockets and related products in collaboration with a team of researchers from A*STAR Singapore Institute of Manufacturing Technology and Clinicians from National University of Singapore. The product helps in preservation and conservation of bone height , volume and density eliminating the need for bone grafting at a later stage. BSI uses a US Food and Drug Administration (FDA) approved Poly lactico glycolic acid (PLGA) for fabrication of scaffold with pre-determined pore architecture and strength. The new method allows re-creation of the scaffold within a short time with the necessary physical and mechanical properties. The scaffold is designed for s! timulating the bone tissue healing and preservation of bone height,volume and density. The degradation rate of the scaffold is tailored to provide the necessary space for bone tissue healing. Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! BioScaff Alvelac - Product Application
Bioscaff™ Alvelac™ is intended to be used as a scaffold for alveolar sockets after tooth extraction. After extraction, as part of the natural healing process, the tooth socket is usually filled with a blood clot and bone is eventually regenerated in a period of approximately two to six months. There would also be some degree of socket contraction and resorption which will result in the reduced bone height of the alveolus. A bio-scaffold is intended to help maintain the original height and width of the socket so that there would be minimal bone loss and a good bone structure. Bioscaff™ Alvelac™ is designed to maintain socket height and width, which will allow for natural bone healing. In addition, it will dissolve in approximately two to six months, and will not act as a source of infection. It will also help to facilitate future dental procedures, such as implants, denture! s or bridges. There would be obvious benefit for any patients contemplating dental implants as there would be less of a need for additional surgery like bone grafting for inadequate bony configuration after dental extraction. After tooth extraction:
BioScaff Alvelac - Other ConsiderationsThere are currently procedures to repair and grow new bone that are part of routine dental surgical care. The four most commonly performed dental bone grafting procedures are nerve repositioning, onlay grafting, ridge augmentation and sinus lift. In addition, other miscellaneous grafting procedures are performed. There are a number of bone graft materials available in dentistry today which can be classified into four different categories: Recipient's Own Bone Autograft is the obtaining of bone graft materials from the patient's body and typically is the best choice of grafting procedure available now. However, autograft has its limitations, which include potential problems such as second site morbidity and patient discomfort in terms of harvesting of a graft from another part of the patients body. Other Human Being's Bone Allograft is the obtaining of bone graft materials from other human being, which can be either a cadaver or living donor. The disadvantage of allograft is that the bone graft materials may be rejected by the recipient's immune system. This results in the patient having to put on anti-rejection medication. Animal Bone Xenograft is the obtaining of bone graft materials from tissue of animal origin, which include bovine (cow's bone) or porcine (pig's bone). Similar to allograft, such bone graft materials may be rejected by the recipient's immune system and anti-rejection medication will have to be used. Synthetic Bone Alloplast is the graft of an inert foreign body (i.e. metal or polymer). It is bio-inert and will n [...] BioScaff Alvelac - A Product Overview Bioscaff™ Alvelac™ is a porous PLGA (poly lactic co glycolic acid) scaffold produced using a proprietary and patented technology. PLGA, a non-toxic, biocompatible and biodegradable polymer, is FDA approved. The scaffold is designed with macro channels and micro-pores. The osteoblast will reproduce on the scaffold. Differentiation will take place subsequently, forming the required bone as the scaffold degrades. It breaks down into lactic acid and glycolic acid, which are metabolised in the body and excreted as carbon dioxide and water. This process typically occurs over a time frame of two to six months. Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Thursday, August 27, 2009Post Dental Extraction Problems: What Happens When a Tooth is Extracted?
Post Dental Extraction Problems: What Happens When a Tooth is Extracted? Tooth extraction can result in several complications:-
Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! BioScaff Alvelac and Tooth Extraction
Post Dental Extraction Problems: What Happens When a Tooth is Extracted? Tooth extraction can result in several complications:-
Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Who is Bio-Scaffold International (BSI)Bio-Scaffold International (BSI), a Singapore based and innovative biotechnology Company, specializes in the development of bio-scaffolds for the replacement of human tissues including bones, joints and ligaments. With the corporate headquarter strategically located in Singapore and through mutually rewarding collaboration with her esteem partners, BSI is well positioned to provide such innovations. BSI's strengths are in its R&D expertise as well as a well trained workforce who contribute as significantly in their primary functions. Every BSI staff are result-oriented professionals and are guided by high personal integrity. Marrying the six prominent components of BSI core values, BSI aims to serve mankind globally based on dedication, professionalism and technical competency. Alvelac and Socket Preservation Understanding uniqueness of Alvelac by watching the video:  Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Sunday, August 23, 2009Bio-Scaffold International Featured in Business Times
BSI featured again in newspaper. This time in The Business Times on Sat, 15 Nov 2008, Pg 15
Heard of Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Bio-Scaffold International Moves to a Bigger Office
Bio-Scaffold International is expanding and has moved to its new office at The Galen in Science Park III.
Do you know who is Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Bio-Scaffold International (BSI) MOU Signed with Saveetha University, India
Signed MOU & commenced additional clinical trials with Saveetha University, India.
Do you know who is Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Bio-Scaffold International (BSI) Clinical Trial in Singapore
Clinical Trial in Singapore approved by National Healthcare Group.
Do you know who is Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Bio-Scaffold International (BSI) In-Vitro and In-Vivo Tests Completed
Completed in-vitro and in-vivo tests.
Do you know who is Doctor Bone? Go to http://www.bio-scaffold.com to find out... See you there ! Bio-Scaffold International (BSI) Implant and Bone Growth
Implant from iliac of rabbit showed bone growth and mineralization inside and outside of the bio-scaffold.
Ask Doctor Bone TODAY at http://www.bio-scaffold.com See you there ! Bio-Scaffold International (BSI) Bio-Scaffold International - New Internal Structure Developed
New internal structure and refined post processing methodology developed.
Ask Doctor Bone TODAY at http://www.bio-scaffold.com See you there ! Bio-Scaffold International (BSI) Saturday, August 22, 2009Bio Scaffold, The Company
A new breakthrough!!
Bio-Scaffold International (BSI) is a http://www.bio-scaffold.com
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